ALK-Rearranged Lung Adenocarcinoma Initially Presenting with Cutaneous Metastases: A Case Report

Only 1% - 12% of patients with lung cancer develop cutaneous metastases. While adenocarcinoma is incredibly common, it rare for a manifestation the disease to be initial presenting complaint. Skin manifestations can difficult identify and appear deceptively benign, leading delays in diagnosis treatment. ALK+ specifically has an increased frequency distant lymph node involvement lymphangitic carcinomatosis relative typical EGFR+ cancer. Herein we report case ALK-rearranged that initially presented as skin metastases neck. Such lesions should identified early, considered potential internal malignancy. Given poor prognosis associated metastases, further diagnostic tests, such imaging or biopsy, done urgency.